Comparing Single-Spin Versus Double-Spin Platelet-Rich Plasma Centrifugation Methods on Thrombocyte Count and Clinical Improvement of Androgenetic Alopecia: A Preliminary, Randomized, Double-Blind Clinical Trial

December 2023 in “ PubMed ”

Lili Legiawati, Shannaz Nadia Yusharyahya, Irma Bernadette, Endi Novianto, Mufqi Handaru Priyanto, Keneyzia Carla Gliselda, Septiana Iriyanty, Rizka Mutiara

platelet-rich plasma PRP androgenetic alopecia AGA thrombocyte count anagen hair telogen hair vellus hair terminal hair

Studysummary This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.

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The study compared single-spin and double-spin platelet-rich plasma (PRP) preparation methods in treating androgenetic alopecia (AGA) in 30 male subjects aged 25 to 59 years. Both methods significantly increased thrombocyte counts by 4 to 5 times from their initial levels, with the single-spin group showing a more significant increase. Both groups also showed significant improvements in hair density, hair rate, and hair count of anagen, telogen, vellus, and terminal hair. The study concluded that both PRP preparation methods have tremendous therapeutic promise for treating AGA, and clinicians may choose either technique.

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This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.

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In this study, researchers found that the prevalence of androgenetic alopecia was higher in their sample compared to other studies in Asian and Caucasian populations, and it was linked with age-related severity.

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research Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men

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