Comparison of the Efficacy of Platelet-Rich Plasma With Topical Minoxidil in Treating Patients With Androgenetic Alopecia: A Systematic Review of Clinical Trials

    July 2025 in “ Skin Health and Disease ”
    Areesha Abid, Faizan Fazal, Haris Mumtaz … Bilal Haider Malik
    Studysummary This study concluded that platelet-rich plasma is nearly as effective as topical minoxidil for treating androgenetic alopecia, with PRP improving hair density and minoxidil boosting terminal hair count.
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    Research cited in this study 26

    1. Efficacy of Platelet-Rich Plasma Versus 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia JCPSP. Journal of the College of Physicians & Surgeons Pakistan · 2024
    2. Platelet-Rich Plasma Therapy Vs Minoxidil in Men with Androgenic Alopecia: Systematic Review International Journal of Social health · 2023
    3. A Randomized Control Trial Comparing the Efficacy of Platelet-Rich Plasma and 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia PubMed · 2023
    4. Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Meta-Analysis Aesthetic Plastic Surgery · 2023
    5. Androgenetic Alopecia: An Update JAAD International · 2023
    6. Platelet-Rich Plasma in Androgenetic Alopecia: Is It Really Worth the Hype? International Journal of Trichology · 2023
    7. Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia Cureus · 2023
    8. Efficacy of Autologous Platelet-Rich Plasma Therapy Versus Topical Minoxidil in Men With Moderate Androgenetic Alopecia: A Randomized Open-Label Trial Journal of Dermatological Treatment · 2023
    9. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    10. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways Frontiers in Medicine · 2022
    11. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review Drug design, development and therapy · 2022
    12. Effectiveness of Platelet-Rich Plasma Therapy in Androgenic Alopecia: A Meta-Analysis Journal of Personalized Medicine · 2022
    13. Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment and the Number of Sessions Required Journal of Cutaneous and Aesthetic Surgery · 2021
    14. Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial Journal of The American Academy of Dermatology · 2020
    15. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    16. Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study Acta dermato-venereologica · 2020
    17. Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial Indian Journal of Dermatology, Venereology and Leprology · 2019
    18. A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women Dermatologic Surgery · 2019
    19. A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia International Journal of Trichology · 2019
    20. Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol International Journal of Women's Dermatology · 2018
    21. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    22. A Split Head Study of Efficacy of Placebo Versus Platelet-Rich Plasma Injections in the Treatment of Androgenic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2017
    23. Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial Journal of Cosmetic and Laser Therapy · 2016
    24. Platelet-Rich Plasma Microneedling Versus 5% Topical Minoxidil in the Treatment of Patterned Hair Loss Journal of the Egyptian Women's Dermatologic Society (Print) · 2016
    25. Topical Minoxidil: Systematic Review and Meta-Analysis of Its Efficacy in Androgenetic Alopecia PubMed · 2015
    26. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007

    Related research 7

    1. Contact Dermatitis Caused by Topical Minoxidil: Allergy or Just Irritation Acta Dermato Venereologica · 2025
    2. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    3. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    4. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    5. Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial 2010
    6. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    7. Androgenetic Alopecia: Treatment Results with Topical Minoxidil Journal of The American Academy of Dermatology · 1987