Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Meta-Analysis

August 2023 in “ Aesthetic Plastic Surgery ”

Meijia Li, Kevin Qu, Lei Qiang, Mingrui Chen, Donghui Bian

platelet-rich plasma androgenic alopecia hair density hair diameter PRP therapy androgenetic alopecia AGA PRP

TLDR Platelet-rich plasma therapy helps increase hair density in male patients with hair loss but doesn't change hair thickness.

The meta-analysis titled "Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia" analyzed 10 trials involving 555 treatment units from 318 participants. The study found that Platelet-rich plasma (PRP) therapy significantly increased hair density in patients with Androgenetic alopecia (AGA), with a mean difference of 25.09 hairs/cm2 (p = 0.002). This effect was more pronounced in male-only trials. However, PRP treatment did not significantly affect hair diameter (p = 0.16). The study concluded that PRP therapy can effectively increase hair density in AGA patients, particularly in males, but does not significantly affect hair diameter. Despite some statistical heterogeneity due to factors like small sample sizes, patient gender, and different PRP treatment regimes, the conclusion was deemed reliable.

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Research cited in this study

19 / 19 results

research Efficacy of Platelet-Rich Plasma in Asians With Androgenetic Alopecia: A Randomized Controlled Trial

September 2022 in “Indian Journal of Dermatology, Venereology and Leprology”

research Effectiveness of Platelet-Rich Plasma Therapy in Androgenic Alopecia: A Meta-Analysis

7 citations , February 2022 in “Journal of Personalized Medicine”

Platelet-Rich Plasma therapy significantly increases hair density in people with Androgenic Alopecia, and works better with more treatments per month and in younger patients.

Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment

research Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment

6 citations , March 2021 in “Journal of Cosmetic Dermatology”

PRP injections promote hair growth and increase hair density in androgenic alopecia.

Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

research Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

13 citations , September 2020 in “International Journal of Molecular Sciences”

PRP therapy and minoxidil combo works best for male hair loss.

research Platelet-Rich Plasma for Androgenetic Alopecia: Efficacy Differences Between Men and Women

10 citations , August 2020 in “Dermatologic Therapy”

PRP improves hair thickness for both genders, but only increases hair density in men.

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33 citations , July 2020 in “Journal of The American Academy of Dermatology”

PRP treatment improves hair density and thickness for alopecia, but needs more research.

research The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial

18 citations , July 2020 in “Journal of The American Academy of Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

research Platelet-Rich Plasma as a Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis

15 citations , May 2020 in “Journal of Dermatological Treatment”

PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.

research Platelet Sonicates Activate Hair Follicle Stem Cells And Mediate Enhanced Hair Follicle Regeneration

16 citations , December 2019 in “Journal of Cellular and Molecular Medicine”

Sonicated platelet-rich plasma boosts hair growth by activating stem cells.

research Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

9 citations , September 2019 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density in male hair loss.

research Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia

39 citations , March 2019 in “Dermatologic Surgery”

PRP therapy increases hair density for androgenetic alopecia.

research The Efficacy of Platelet-Rich Plasma in Hair Restoration and Facial Aesthetics: A Systematic Review and Meta-Analysis

31 citations , January 2019 in “Journal of Cutaneous Medicine and Surgery”

Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.

research Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia

37 citations , May 2018 in “Journal of Cosmetic Dermatology”

PRP shows promise for hair loss treatment, but needs standardized preparation and composition.

The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

research The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

52 citations , May 2017 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

research Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

136 citations , February 2017 in “International Journal of Molecular Sciences”

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

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research Use of Autologous Platelet-Rich Plasma in Androgenetic Alopecia in Women: A Systematic Review and Meta-Analysis

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