The Hair Loss Encyclopedia

The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years

January 2018 in “ Italian journal of dermatology and venereology ”

Mauro Barbareschi

minoxidil androgenetic alopecia telogen phase anagen phase hair follicles propylene glycol Rogaine

TLDR Minoxidil effectively stimulates hair growth in androgenetic alopecia.

Minoxidil had been used for over 30 years as a hair growth stimulator, although its precise mechanism was not fully understood. It was known to shorten the telogen phase, accelerate the telogen-exogen phase, and induce premature entry of resting hair follicles into the anagen phase, while also increasing hair follicle size. Scientific literature confirmed the efficacy of topically applied minoxidil in humans, with patients showing a significant increase in non-vellus hair count. Minoxidil formulations with low concentrations of propylene glycol were developed for better cosmetic acceptance and dermatological safety. Overall, minoxidil remained a key treatment for androgenetic alopecia.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 676 upvotes 5 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Why don't Minoxidil regenerated hairs become terminal on the head?

in Minoxidil 102 upvotes 2 weeks ago

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 75 upvotes 9 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community How does hair loss and recovery work?

in Chat 12 upvotes 7 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community The Finasteride Shed is real.

in Finasteride/Dutasteride 159 upvotes 6 months ago

Increasing finasteride dosage can cause significant hair shedding initially. Users suggest adding minoxidil or switching to dutasteride for better results.

community Hair greed made me switch to Dut too early

in Chat 42 upvotes 1 month ago

The user switched from finasteride to dutasteride for hair loss but faced increased shedding and anxiety, regretting not staying with finasteride longer. Other users shared mixed experiences, advising patience with dutasteride, as it may take up to a year to show results.

Related Research

8 / 8 results

Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

1 citations, August 2022 in “JAAD case reports”

Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.

research Male Androgenetic Alopecia

1 citations, November 2021 in “CRC Press eBooks”

Common hair loss in men can be treated with minoxidil or finasteride.

Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect

research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect

4 citations, May 2019 in “Skin Research and Technology”

Finasteride helps hair growth but stopping it causes faster hair loss.

Hair Loss (Alopecia or Baldness)

research Hair Loss (Alopecia or Baldness)

June 2018

Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.

A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth

research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth

30 citations, May 2018 in “Experimental Dermatology”

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Treatments of Hereditary Hair Loss (Alopecia)

research Treatments of Hereditary Hair Loss (Alopecia)

April 2018

Some treatments like minoxidil, finasteride, and surgery can help with hereditary hair loss.

research Male Pattern Baldness: An Update

January 2009 in “Revista de Ciências Médicas”

Male pattern baldness is a genetic condition causing hair loss, with limited but improving treatment options.

The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil

research The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil

18 citations, April 1986 in “International Journal of Cosmetic Science”

Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.