The Role of Sesbania Grandiflora-Derived Biotin and Bambusa Arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study

    July 2025 in “ Cureus ”
    Maheshvari Patel, Jit Maheshvari, Nayan Patel
    Studysummary In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
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    Research cited in this study 11

    1. Advancing Hair Regrowth Assessment: Development and Standardization of Methods for Evaluating New Hair Growth, Hair Keratin Levels, and Scalp Health in Androgenetic Alopecia Patients Cureus · 2025
    2. Biotin for Hair Loss: Teasing Out the Evidence PubMed · 2024
    3. Revitalizing Skin, Hair, Nails, And Muscles: Unlocking Beauty And Wellness With Vegan Collagen Journal of Cosmetic Dermatology · 2024
    4. Uncombable Hair Improved by Biotin JEADV Clinical Practice · 2023
    5. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    6. An Open-Label Experience Trial to Evaluate the Effects of a Novel Supplement and Hair Serum Combination on Hair, Skin, and Nails in Healthy Women Current developments in nutrition · 2021
    7. A Randomized Double-Blind Evaluation of a Novel Biotin and Silicon Ingredient Complex on the Hair and Skin of Healthy Women Journal of clinical & experimental dermatology research · 2021
    8. Response to: Rethinking Biotin Therapy for Hair, Nail, and Skin Disorders Journal of The American Academy of Dermatology · 2018
    9. Nutritional Correction for Hair Loss, Thinning of Hair, and Achieving New Hair Regrowth 2017
    10. A Review of the Use of Biotin for Hair Loss Skin appendage disorders · 2017
    11. Use of Silicon for Skin and Hair Care: An Approach to Chemical Forms Available and Efficacy Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2016