Hair Regeneration in Androgenetic Alopecia Using Secretome of Adipose-Derived Stem Cells and Minoxidil: A Comparative Study of Three Groups

    April 2024
    Lili Legiawati, Irma Bernadette S. Sitohang, Shannaz Nadia Yusharyahya … Brigitta Cindy Lauren
    Studysummary This study found that treatments with adipose-derived stem cell secretome and minoxidil significantly improved hair growth in androgenetic alopecia, with the combination therapy showing the greatest improvement over 12 weeks.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on researchsquare.com →
    Discuss this study in the Community →

    Research cited in this study 21

    1. Psychosocial Impact of Androgenetic Alopecia on Men: A Systematic Review and Meta-Analysis Psychology, Health & Medicine · 2023
    2. Combination of Adipose-Derived Stem Cell Conditioned Media and Minoxidil for Hair Regrowth in Male Androgenetic Alopecia: A Randomized, Double-Blind Clinical Trial Stem Cell Research & Therapy · 2023
    3. Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    4. Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia Dermatology and therapy · 2023
    5. Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature Regenerative Therapy · 2022
    6. Androgenetic Alopecia: Clinical Features and Trichoscopy DOAJ (DOAJ: Directory of Open Access Journals) · 2022
    7. Hair Disorder in Dr. Cipto Mangunkusumo Cosmetic Dermatology and Venereology Outpatient Clinic of Jakarta, Indonesia: A Socio-Demographic and Clinical Evaluation Dermatology Reports · 2022
    8. Prevalence of Early-Onset Androgenetic Alopecia and Its Relation with Lifestyle and Dietary Habits Italian journal of dermatology and venereology · 2022
    9. Mesenchymal Stem Cell Secretome for Dermatology Application: A Review Clinical, Cosmetic and Investigational Dermatology · 2021
    10. Implications of Cigarette Smoking on Early-Onset Androgenetic Alopecia: A Cross-Sectional Study Journal of Cosmetic Dermatology · 2020
    11. Early-Onset Androgenetic Alopecia in China: A Descriptive Study of a Large Outpatient Cohort Journal of International Medical Research · 2020
    12. Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium Dermatologic Surgery · 2019
    13. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    14. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    15. Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey Anais Brasileiros De Dermatologia · 2017
    16. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    17. The Latest Advance in Hair Regeneration Therapy Using Proteins Secreted by Adipose-Derived Stem Cells The American Journal of Cosmetic Surgery · 2012
    18. Efficacy and Safety of 3% Minoxidil Versus Combined 3% Minoxidil / 0.1% Finasteride in Male Pattern Hair Loss: A Randomized, Double-Blind, Comparative Study PubMed · 2012
    19. A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women Journal of The American Academy of Dermatology · 2011
    20. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    21. Male-Pattern Hair Loss in Norwegian Men: A Community-Based Study Dermatology · 2000

    Related research 8

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit? Clinical and Experimental Dermatology · 2022
    3. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    4. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    5. Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial 2010
    6. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    7. Androgenetic Alopecia: Treatment Results with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    8. Topical Minoxidil Therapy and Hair Regrowth Archives of Dermatology · 1985