Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis
January 2004
in “
Dermatologic Surgery
”
hair shaft elongation hair follicle micrografts HEPES-buffered DMEM PBS aminoguanidine 14,15-epoxy-eicosatrienoic acid apoptotic cell death serum-induced apoptotic cell death storage buffers ACD inhibitors pH changes free radical generation key enzymes hair restoration surgery follicle cell viability graft survival HSE AMG 14,15-EET ACD
Studysummary This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
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