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research The effects of phosphodiesterase 3 (PDE3) inhibitor on hair follicle cell viability and hair growth

1 citations , January 2020 in “Seoul National University Open Repository (Seoul National University)”

This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.

research Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis

10 citations , January 2004 in “Dermatologic Surgery”

This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.

research Cell Viability and Hair Growth Effect on 3T3-L1 Cells of Ethanol Extract from Calendula officinalis L. Flower, Phellinus linteus Fruit Body and Houttuynia cordata Thunb. Whole Plant

2 citations , December 2017 in “Korean Journal of Medicinal Crop Science”

This study found that 70% ethanol extract of Houttuynia cordata promoted hair growth in laboratory cell models, suggesting potential use in developing hair care products.

research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1

February 2023 in “International Journal of Molecular Sciences”

This study found that exosomes derived from dermal papilla cells can enhance the proliferation of hair follicle stem cells by stimulating the LEF1 pathway, offering insights into hair follicle growth regulation.

research Assessment of hair follicle viability in artificial media before transplantation

September 2025 in “Голова и шея.”

This study examined human hair follicles exposed to different artificial media and found that Dimephosphone solution better preserved the potassium-sodium ion balance, suggesting its potential advantage for short-term graft storage compared to standard saline, which caused significant potassium "washout.

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Community Join

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community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

10 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for alopecia treatment. They enhance cell viability, maintain stemness, and induce hair growth without teratoma formation.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

11 upvotes 2 years ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

11 upvotes 3 years ago

Fibrin hydrogels, when combined with stem cells, can induce hair follicle regeneration and show potential for treating alopecia. The study demonstrated successful hair growth in mice without adverse effects.

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Learn

9 / 44 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Platelet-Rich Plasma

Concentrate of your own blood platelets, injected into the scalp

learn Stem Cell Factor

Does stem cell factor help activate dormant hair follicles? Lab and mouse studies link stem cell factor to hair colour; it has not been shown to reactivate dormant hair follicles in people.

learn Valproic acid

What biological mechanisms related to hair follicles are linked to valproic acid in experimental treatments? In cell and mouse studies, valproic acid alters signalling linked to hair growth. This has not been shown to help people outside one small trial, and oral valproate carries a boxed warning and can itself cause hair loss.

learn KY19382

How does KY19382 actually stimulate dormant hair follicles to grow again? In mouse and cell studies, KY19382 reactivated hair follicles via Wnt/β-catenin signalling; it has never been tested in humans.

learn zinc PCA

What does zinc do in hair follicles, and does low zinc affect hair loss? Zinc is needed for cell growth, including in hair follicles, and studies link low blood zinc with some types of hair loss. Zinc supplements have been tested only in small studies of people who were low in zinc.

learn Procyanidin

What is Procyanidin, and how does it encourage hair growth at the follicle level? In mouse cell and animal studies, procyanidin B-2 increased hair-cell growth. Small human trials, all run by the company that developed the ingredient, reported modest gains; it is not a proven or approved hair-loss treatment.

learn Exosomes

Tiny cell-derived particles offered by clinics as an injectable treatment

learn SCUBE3

Signalling protein made in the hair follicle

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