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Glossary Terminal Hair Count

number of thick, pigmented hairs on the body

Terminal Hair Count refers to the number of thick, pigmented hairs on the scalp or other parts of the body. These hairs are fully developed and contrast with finer, lighter vellus hairs. In clinical settings, measuring the terminal hair count can help assess the effectiveness of treatments for hair loss conditions like androgenetic alopecia.

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Research

5 / 1000+ results

Mesenchymal Stem Cell-Derived Exosomes Can Effectively Improve Hair Count and Terminal Hair Diameter in Androgenetic Alopecia

research Mesenchymal Stem Cell-Derived Exosomes Can Effectively Improve the Hair Count and Terminal Hair Diameter in Androgenetic Alopecia

June 2025 in “Research Square (Research Square)”

This study reported that intradermal injections of stem cell exosomes appeared safe and significantly improved hair density and diameter in male androgenetic alopecia patients over 24 weeks, suggesting the therapy may be a promising new treatment option worthy of further investigation.

Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women

research Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women

145 citations , December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”

Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.

research Hair Counts from Normal Scalp Biopsy in Taiwan

24 citations , September 2012 in “Dermatologic Surgery”

The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.

research Evaluation of Hair Follicle Counts of Occipital Scalp Biopsies from Male Hair Transplant Patients in Thailand

1 citations , February 2023 in “Siriraj Medical Journal/San Sirirat”

This study found that Thai males with androgenic alopecia displayed lower average hair density in the occipital scalp compared to other Asian populations, but higher than those with advanced AGA.

Effects of Platelet-Rich Plasma on Hair Follicle Count and Hair Ratios in Androgenic Alopecia: Alone or Combined with Other Treatments

research Effects of platelet-rich plasma application on hair follicle count, telogen/anagen ratio, and miniaturized hair ratio in patients with androgenic alopecia: alone or in combination with other treatments

July 2025 in “Journal of Dermatological Treatment”

This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.

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Community Join

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community I understand this topic has been discussed countless times, but hair loss is the most brutal experience for men.

in Chat 343 upvotes 1 year ago

Hair loss significantly affects men's confidence and mental health. Common treatments include finasteride, dutasteride, and minoxidil, with some considering hair transplants.

community Most studies seem to say the vast majority of increase in hair count occurs in the first 12 weeks, why does everyone say you need to wait years to know whether fin/dut are working?

in Finasteride/Dutasteride 66 upvotes 1 year ago

Finasteride and dutasteride can show initial hair count increases within 12 weeks, but visible improvements often take longer, with many users reporting noticeable changes after a year or more. While early results may be seen under a microscope, significant cosmetic improvements typically require more time for hair to thicken and become visibly denser.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways.

4 upvotes 3 weeks ago

Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.

community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.

in Research/Science 55 upvotes 1 year ago

PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.

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Learn

6 / 6 results

learn Clascoterone

How long does it take for clascoterone to show results on hair growth? Clascoterone is not approved for hair loss; it is investigational. In the trials reported so far, application was twice daily and increases in terminal hair count were reported at around 6 months, with more sustained change reported between 6 and 12 months.

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss