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Glossary Terminal Hair Growth

development of thick, pigmented hairs replacing finer vellus hairs

Terminal hair growth refers to the development of thick, pigmented hairs that replace the finer, lighter vellus hairs during puberty or in response to hormonal changes. These mature hairs are typically found on the scalp, face, armpits, and pubic area, and are influenced by androgens, particularly testosterone.

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Research

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research Double-blind, randomized, placebo-controlled trial of a cream containing theStryphnodendron adstringens(Martius) Coville bark extract for suppressing terminal hair growth

9 citations , January 2009 in “Journal of the European Academy of Dermatology and Venereology”

This study found that a cream containing 6.0% Stryphnodendron adstringens bark extract effectively reduced terminal hair growth and improved skin conditions in women with excessive terminal hair.

research An unusual terminal hair growth on the nose tip associated with gefitinib therapy

4 citations , March 2007 in “British Journal of Dermatology”

This case report observed that terminal hair growth on the nose tip was associated with gefitinib treatment in a 65-year-old woman with lung adenocarcinoma.

research Reduced Linear Hair Growth Rates of Vellus and of Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice

23 citations , December 1991 in “Annals of the New York Academy of Sciences”

This study reported that human balding scalp grafted onto nude mice showed reduced linear growth rates of both vellus and terminal hairs.

research Nevus comedonicus with lesional growth of terminal hair: An unusual case

September 2024 in “The Journal of Dermatology”

In this study, researchers reported a rare case of nevus comedonicus with hair growth in a 26-year-old male, challenging prior reports that affected lesions typically lack the capability to develop terminal hair.

Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression

research Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras‐dependent up‐regulation of KGF expression

51 citations , December 2003 in “The FASEB Journal”

This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.

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Community Join

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community 1 year on oral minoxidil 5mg and finasteride 1 mg on alternate days. Started derma rolling 1 month back. Will the vellus hair in temple become terminal? Also seeing good hair growth and reduced hairfall after I started Biotin and other hair growth supplements

in Is this regrowth? 12 upvotes 1 year ago

The conversation discusses hair regrowth treatments, including oral minoxidil 5mg and finasteride 1mg on alternate days, along with derma rolling, biotin, and other supplements. The user reports good hair growth and reduced hair fall, with no side effects from oral minoxidil except increased body hair.

community Turning vellus hairs into terminal hair

in Research/Science 12 upvotes 1 year ago

People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.

in Research/Science 55 upvotes 1 year ago

PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.

community Why don't Minoxidil regenerated hairs become terminal on the head?

in Minoxidil 101 upvotes 1 year ago

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

community My 6 month mark. Already have some terminal hairs starting to come in.

27 upvotes 9 months ago

The user shared progress pictures showing hair growth after six months of using topical minoxidil twice daily, finasteride once daily, derma rolling every four days, and initially taking zinc and vitamin D. They also used scalp massaging techniques with minoxidil.

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Learn

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learn Clascoterone

How long does it take for clascoterone to show results on hair growth? Clascoterone is not approved for hair loss; it is investigational. In the trials reported so far, application was twice daily and increases in terminal hair count were reported at around 6 months, with more sustained change reported between 6 and 12 months.

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glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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