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research Improvement in scalp hair growth in androgen‐deficient women treated with testosterone: a questionnaire study

21 citations , October 2011 in “British Journal of Dermatology”

This study found that subcutaneous testosterone therapy improved scalp hair growth in a majority of androgen-deficient women who previously reported hair thinning and did not report hair loss as a side effect.

Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type Over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair Are Risk Factors

research Cutaneous malignant melanoma incidences analyzed worldwide by skin type over advancing age of males and females: Evidence estrogen and androgenic hair are risk factors

3 citations , December 2016 in “Journal of epidemiological research”

In this study, only European-ancestry females showed a linear increase in cutaneous malignant melanoma risk with age, potentially due to the loss of HPV-infected androgenic follicles after menopause.

research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research

April 2026 in “Journal of Dermatological Science”

This study highlights that hair-bearing organoids derived from embryonic stem cells can effectively model androgenic alopecia conditions and test the efficacy of anti-hair loss treatments.

Evaluation of Hair Growth Promoting Activity of Sansevieria Trifasciata P. on Androgenic Alopecia in Male Rabbits

research Evaluation of Hair Growth Promoting Activity of Sansevieria Trifasciata P. on Alopecia Androgenic Rabbit Male

January 2021 in “International journal of pharmaceutical research”

In this study, the researchers found that the ethyl acetate fraction of Sansevieria trifasciata P. (20%) was just as effective as minoxidil (2%) in promoting hair growth in male rabbits, with notable results in hair follicle proliferation and a favorable anagen to telogen ratio.

research The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp.

January 2010

This study reported that paracrine factors, such as IGF-I and SCF, were reduced in balding hair follicles compared to non-balding ones, while inhibitory factors like TGFß-1 were increased, providing insights into the androgen action in hair follicles.

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learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Spironolactone

Who can safely use spironolactone for hair thinning and androgen-related hair loss? Women with androgen-related hair loss can safely use spironolactone under medical supervision.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Procyanidin

Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia? Procyanidin-based hair tonics may promote hair growth but lack definitive evidence for AGA.

learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

learn GT20029

research compound made to degrade androgen receptors in scalp

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

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Community Join

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community Androgen degraders for hair loss

61 upvotes 2 years ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community Updated hairloss treatments for Androgenetic Alopecia

659 upvotes 1 year ago

The conversation discusses treatments for Androgenetic Alopecia, including Minoxidil, finasteride, RU58841, and topical caffeine. It emphasizes that there are multiple treatment options available in 2025.

community Anti-Androgens causing hairline to recede?

in Research/Science 5 upvotes 2 years ago

Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.

community Debunking Androgenetic Theory (Hair Transplants)

in Research/Science 25 upvotes 2 years ago

The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

community Iron Deficiency Hair Loss vs Androgenetic Alopecia

5 upvotes 3 years ago

Iron deficiency can mimic androgenetic alopecia (AGA) and cause hair loss, but it is rare in men. Recovery is possible with supplements if iron deficiency is the cause, but genetic hair loss may still progress.

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