Regenerative Biotechnologies in Plastic Surgery: A Multicentric, Retrospective, Case-Series Study on the Use of Microneedling with Low-Level Light/Laser Therapy as a Hair Growth Boost in Patients Affected by Androgenetic Alopecia

December 2021 in “ Applied sciences ”

Pietro Gentile, Simone Garcovich, Soo-Jung Lee, Sangbum Han

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research The Effectiveness of Low-Level Light/Laser Therapy on Hair Loss

8 citations , September 2021 in “Facial plastic surgery & aesthetic medicine”

Low-level light/laser therapy is effective in treating male and female pattern hair loss without side effects.

research Low-Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men With Androgenetic Alopecia and Boosts Minoxidil 2% for Sustainable Hair Regrowth

4 citations , May 2021 in “Lasers in Surgery and Medicine”

Light therapy reduces scalp inflammation, boosts hair regrowth with Minoxidil 2%.

research Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis

6 citations , January 2021 in “Annals of Dermatology”

650 nm red light helps hair grow and prevents hair loss by affecting certain genes and biological processes.

research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

20 citations , July 2020 in “Expert Opinion on Biological Therapy”

Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.

research Photobiomodulation for the Management of Alopecia: Mechanisms of Action, Patient Selection, and Perspectives

34 citations , September 2019 in “Clinical, Cosmetic and Investigational Dermatology”

Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.

research Low-Level Laser Therapy for the Treatment of Androgenetic Alopecia in Thai Men and Women: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Trial

45 citations , August 2019 in “Lasers in Medical Science”

LLLT promotes hair growth and improves hair density safely in men and women.

research A Randomized, Investigator-Blinded, Controlled, Split-Scalp Study of the Efficacy and Safety of a 1550-nm Fractional Erbium-Glass Laser, Used in Combination with Topical 5% Minoxidil Versus 5% Minoxidil Alone, for the Treatment of Androgenetic Alopecia

29 citations , April 2019 in “Lasers in Medical Science”

Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.

research Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial

31 citations , November 2018 in “Dermatologic Surgery”

Low-level light therapy safely improves hair coverage, thickness, and count in androgenetic alopecia patients.

research Photodynamic and Photobiological Effects of Light-Emitting Diode Therapy in Dermatological Disease: An Update

62 citations , July 2018 in “Lasers in Medical Science”

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

research Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review

41 citations , February 2018 in “Lasers in Medical Science”

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

research Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)

33 citations , June 2017 in “Dermatologic Surgery”

Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.

research Comparison of the Effects of 665 nm Low-Level Diode Laser Hat Versus a Combination of 665 nm and 808 nm Low-Level Diode Laser Scanner on Hair Growth in Androgenic Alopecia

24 citations , May 2017 in “Journal of Cosmetic and Laser Therapy”

The laser scanner device was more effective at increasing hair density than the laser hat in treating androgenic alopecia.

research Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study

34 citations , May 2017 in “Lasers in Surgery and Medicine”

Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.

research Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

136 citations , February 2017 in “International Journal of Molecular Sciences”

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

research Low-Level Laser Therapy as a Treatment for Androgenetic Alopecia

47 citations , January 2017 in “Lasers in Surgery and Medicine”

Low-level laser therapy may improve hair regrowth and thickness for androgenetic alopecia, but more research is needed.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research The Growth of Human Scalp Hair in Females Using Visible Red Light Laser and LED Sources

81 citations , August 2014 in “Lasers in Surgery and Medicine”

Red light therapy is safe and effectively increases hair growth in women with hair loss.

research Use of Low-Level Laser Therapy as Monotherapy or Concomitant Therapy for Male and Female Androgenetic Alopecia

45 citations , April 2014 in “International Journal of Trichology”

Low-level laser therapy helps male and female hair loss alone or with other treatments.

research Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study

147 citations , January 2014 in “American Journal of Clinical Dermatology”

Laser device increases hair density, safe for treating hair loss in men and women.

research The Growth of Human Scalp Hair Mediated by Visible Red Light Laser and LED Sources in Males

117 citations , September 2013 in “Lasers in Surgery and Medicine”

Red light therapy at 655 nm significantly improved hair growth in men with hair loss.

research Low-Level Laser Therapy for Treatment of Hair Loss

165 citations , August 2013 in “Lasers in Surgery and Medicine”

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

research Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial

106 citations , August 2013 in “Dermatologic Surgery”

Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.

research Effects of the Lexington LaserComb on Hair Regrowth in the C3H/HeJ Mouse Model of Alopecia Areata

81 citations , July 2011 in “Lasers in Medical Science”

The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.

research Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia

52 citations , June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity”

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

research The Use of Low-Level Light for Hair Growth: Part I

90 citations , January 2009 in “Journal of cosmetic and laser therapy”

Low-level laser therapy might help hair growth, but more research is needed.

research HairMax LaserComb Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia

160 citations , January 2009 in “Clinical Drug Investigation”

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

research Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

75 citations , August 2003 in “International journal of cosmetic surgery and aesthetic dermatology”

The HairMax LaserComb made hair grow more and get stronger for people with hair loss.

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , September 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Treatment of Hair Loss

370 citations , September 1999 in “The New England Journal of Medicine”

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.