Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Areata: A Randomized Double-Blinded Parallel-Group Study

    April 2020 in “ Dermatology and Therapy ”
    Fabio Rinaldi, Anna Trink, Daniela Pinto
    Studysummary In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 27

    1. Microbiome in the Hair Follicle of Androgenetic Alopecia Patients PLOS ONE · 2019
    2. Scalp Bacterial Shift in Alopecia Areata PloS one · 2019
    3. Randomized Controlled Trial on a PRP-Like Cosmetic with Biomimetic Peptides for the Treatment of Alopecia Areata Journal of Dermatological Treatment · 2018
    4. Meta-Analysis on Evidence of Platelet-Rich Plasma for Androgenetic Alopecia International Journal of Trichology · 2018
    5. Immune Privilege Collapse And Alopecia Development: Is Stress A Factor Skin Appendage Disorders · 2017
    6. A Review of Monochromatic Light Devices for the Treatment of Alopecia Areata Lasers in Medical Science · 2017
    7. Platelet-Rich Plasma—An 'Elixir' for Treatment of Alopecia: Personal Experience on 117 Patients with Review of Literature Stem cell investigation · 2017
    8. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    9. Treating Alopecia Areata: Current Practices Versus New Directions American journal of clinical dermatology · 2016
    10. Alopecia Areata: What’s New in Epidemiology, Pathogenesis, Diagnosis, and Therapeutic Options? Journal of dermatological science · 2016
    11. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    12. Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth Annals of Dermatology · 2016
    13. Effects of the Biomimetic Peptide Sh-Polypeptide 9 (CG-VEGF) on Cocultures of Human Hair Follicle Dermal Papilla Cells and Microvascular Endothelial Cells Experimental Dermatology · 2015
    14. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    15. Lack of Collagen VI Promotes Wound-Induced Hair Growth Journal of Investigative Dermatology · 2015
    16. The Role of Hair Follicle Immune Privilege Collapse in Alopecia Areata: Status and Perspectives Journal of Investigative Dermatology Symposium Proceedings · 2013
    17. A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata British Journal of Dermatology · 2013
    18. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    19. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    20. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011
    21. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    22. Clinical Significance of Dermoscopy in Alopecia Areata: Analysis of 300 Cases International Journal of Dermatology · 2008
    23. Thymosin Beta 4 Induces Hair Growth Via Stem Cell Migration And Differentiation Annals of the New York Academy of Sciences · 2007
    24. The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro Archives of Pharmacal Research · 2007
    25. Videodermoscopy in the Evaluation of Hair and Scalp Disorders Journal of The American Academy of Dermatology · 2006
    26. Thymosin Beta 4 Increases Hair Growth by Activation of Hair Follicle Stem Cells The FASEB Journal · 2003
    27. Chemical Agents and Peptides Affect Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993

    Related research 3

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018