Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Areata: A Randomized Double-Blinded Parallel-Group Study

April 2020 in “ Dermatology and Therapy ”

Fabio Rinaldi, Anna Trink, Daniela Pinto

postbiotics platelet-rich plasma alopecia areata Severity of Alopecia Tool bioactive peptides microbial metabolites hair growth disorders PRP SALT

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Studysummary In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness. Our plain-language summary of this paper — not a Tressless recommendation.

In a study from April 11, 2020, involving 160 participants with Alopecia areata (AA), a cosmetic product containing postbiotics and mimicking platelet-rich plasma (PRP) was tested for its effectiveness in treating AA. The participants were divided into two groups, with one receiving the active cosmetic product and the other a placebo. The Severity of Alopecia Tool (SALT) score was used to measure treatment efficacy, and after 2 and 3 months, the group using the active product showed significant improvement in SALT scores (61.04% ± 3.45% at 2 months and 69.56% ± 4.32% at 3 months, both p < 0.0001), while the placebo group did not show significant changes. The study concluded that the PRP-like cosmetic product with postbiotics is effective in treating AA and suggested that bioactive peptides and microbial metabolites could be a new therapeutic approach for hair growth disorders.

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Research cited in this study

27 / 27 results

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