Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Areata: A Randomized Double-Blinded Parallel-Group Study

    April 2020 in “ Dermatology and Therapy
    Fabio Rinaldi, Anna Trink, Daniela Pinto
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    TLDR The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.
    In a study from April 11, 2020, involving 160 participants with Alopecia areata (AA), a cosmetic product containing postbiotics and mimicking platelet-rich plasma (PRP) was tested for its effectiveness in treating AA. The participants were divided into two groups, with one receiving the active cosmetic product and the other a placebo. The Severity of Alopecia Tool (SALT) score was used to measure treatment efficacy, and after 2 and 3 months, the group using the active product showed significant improvement in SALT scores (61.04% ± 3.45% at 2 months and 69.56% ± 4.32% at 3 months, both p < 0.0001), while the placebo group did not show significant changes. The study concluded that the PRP-like cosmetic product with postbiotics is effective in treating AA and suggested that bioactive peptides and microbial metabolites could be a new therapeutic approach for hair growth disorders.
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