Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth

    January 2016 in “ Annals of Dermatology ”
    Weon Ju Lee, Hyun Bo Sim, Yong Hyun Jang, Seok Jong Lee, Do Won Kim, Soon Ho Yim
    Image of study
    TLDR A complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide may help increase hair count in male pattern hair loss without side effects.
    In a 2016 study, 45 male patients with male pattern hair loss were treated with a complex of 5-aminolevulinic acid (5-ALA) and glycyl-histidyl-lysine (GHK) peptide (ALAVAX) to assess its efficacy and safety. The patients were divided into three groups: group A received ALAVAX 100 mg/ml, group B received ALAVAX 50 mg/ml, and group C received a placebo, all applied once daily for 6 months. Group B showed a significant increase in hair count with an average of 71.5 hairs, which was statistically significant compared to group C's 9.6 hairs. Group A also experienced an increase of 52.6 hairs. Satisfaction was highest in group A at 26.7%. No significant differences were found in hair length and thickness among the groups, and no adverse events were reported. The study concluded that the 5-ALA and GHK peptide complex could be a complementary treatment for male pattern hair loss.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 1000+ results

      community How does low level laser therapy?

      in Chat  5 upvotes 10 months ago
      Low-level laser therapy (LLLT) is debated for hair regrowth, with some users suggesting it should be combined with treatments like minoxidil and finasteride for effectiveness. Many users express skepticism about LLLT's efficacy and cost, emphasizing the need for the correct wavelength and quality devices.

      community 5 months on min+fin and letting my hair grow

      in Progress Pictures  224 upvotes 1 day ago
      The user shared progress pictures after 5 months of using topical minoxidil (1ml per day) and oral finasteride (1mg per day) for hair growth, with no side effects reported. The user also mentioned having a hair transplant in December and uses pH-neutral baby shampoo.

      community 5 months of dut after 1 year of fin

      in Progress Pictures  8 upvotes 3 days ago
      The user has been using dutasteride for 5 months and recently added finasteride, RU58841, and minoxidil, but is still experiencing significant hair shedding. Despite concerns, other users think the user's hair looks good and suggest continuing with finasteride.

      community 5 months into 0.5mg Dutasteride 3x a week + 5mg Oral Minoxidil

      in Progress Pictures  58 upvotes 2 weeks ago
      A user is treating hair loss with 0.5mg Dutasteride three times a week, 5mg oral Minoxidil daily, and topical finasteride and minoxidil, seeing some improvement but insufficient density. They are considering increasing Dutasteride dosage and addressing high estradiol levels, while also trying to quit vaping.

      community 5 month progress on Locklabs oral tablet

      in Progress Pictures  19 upvotes 3 weeks ago
      The user experienced significant hair regrowth over five months using Locklabs oral tablets, with no side effects and only a minor shed. They dye their hair black to cover natural blonde, which may affect perceived hair density.

    Related Research

    7 / 7 results