72 citations
,
December 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
18 citations
,
May 2012 in “Experimental Dermatology” No link found between specific genes and female pattern hair loss.
45 citations
,
March 2012 in “Experimental Dermatology” Human hair follicles switch between active and resting phases unpredictably.
36 citations
,
November 2011 in “British Journal of Dermatology” White hair grows thicker and faster than black hair due to higher activity of growth-related genes and proteins.
51 citations
,
November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
87 citations
,
May 2011 in “Australasian Journal of Dermatology” Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
56 citations
,
April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
149 citations
,
June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
175 citations
,
December 2009 in “PLOS ONE” Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
234 citations
,
November 2009 in “American journal of human genetics” Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
45 citations
,
July 2009 in “Journal of human genetics” A gene variation is linked to hair thickness in Asians.
30 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
98 citations
,
December 2008 in “Human mutation” A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
111 citations
,
October 2008 in “Nature Genetics” Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
209 citations
,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
62 citations
,
March 2008 in “American Journal of Human Genetics” Hair loss gene found on chromosome 3q26.
210 citations
,
February 2008 in “Nature genetics” Mutations in the P2RY5 gene cause autosomal recessive woolly hair.
85 citations
,
October 2007 in “International Journal of Dermatology” Curly hair shape is due to uneven growth patterns in the hair follicle.
210 citations
,
May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
20 citations
,
September 2005 in “Journal of Cutaneous Pathology” The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
108 citations
,
October 2003 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin makes hair follicles stronger.
49 citations
,
June 2003 in “European journal of cardiovascular prevention & rehabilitation” Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
11 citations
,
February 2002 in “International Journal of Cosmetic Science” Recent findings show that hair growth and color are controlled by a complex network of signals in the hair follicle.
116 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
115 citations
,
September 2000 in “The Lancet” Early hair loss may indicate risk of insulin resistance.
416 citations
,
September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
130 citations
,
May 1988 in “Journal of The American Academy of Dermatology” "Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.