The Biology of Hair Diversity

    Gillian Westgate, Natalia V. Botchkareva, Desmond J. Tobin
    Studysummary This review explores genetic and lifestyle factors influencing hair diversity and reports no new findings, calling attention to the potential for future discoveries in genetic and epigenetic research.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 37

    1. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012
    2. Selected Variants of the Steroid-5-Alpha-Reductase Isoforms SRD5A1 and SRD5A2 and the Sex Steroid Hormone Receptors ESR1, ESR2, and PGR: No Association with Female Pattern Hair Loss Identified Experimental Dermatology · 2012
    3. The Human Hair Follicle, A Bistable Organ? Experimental Dermatology · 2012
    4. Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness British Journal of Dermatology · 2011
    5. Hair Greying Is Associated With Active Hair Growth British Journal of Dermatology · 2011
    6. Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update Australasian Journal of Dermatology · 2011
    7. Grey Hair: Clinical Investigation Into Changes in Hair Fibres With Loss of Pigmentation in a Photoprotected Population International Journal of Cosmetic Science · 2011
    8. EZH1 and EZH2 Co-Govern Histone H3K27 Trimethylation and Are Essential for Hair Follicle Homeostasis and Wound Repair Genes & Development · 2011
    9. Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile Involving Catalase ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    10. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    11. Chronological Aging of Human Hair Keratin Fibers International Journal of Cosmetic Science · 2010
    12. Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74, a Potential Determinant of Human Hair Texture The American Journal of Human Genetics · 2010
    13. Why Some Women Look Young for Their Age PLOS ONE · 2009
    14. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    15. FGFR2 Is Associated With Hair Thickness In Asian Populations Journal of human genetics · 2009
    16. Recent Positive Selection of a Human Androgen Receptor/Ectodysplasin A2 Receptor Haplotype and Its Relationship to Male Pattern Baldness Human Genetics · 2009
    17. Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11 Nature Genetics · 2008
    18. Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
    19. Androgens and Hair Growth Dermatologic Therapy · 2008
    20. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    21. Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form Human mutation · 2008
    22. Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008
    23. Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair Nature genetics · 2008
    24. Human Hair Keratin Network And Curvature International Journal of Dermatology · 2007
    25. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    26. Expression of Androgen Receptor Coactivator ARA70/ELE1 in Androgenic Alopecia Journal of Cutaneous Pathology · 2005
    27. Comparative Aspects of the Inner Root Sheath in Adult and Developing Hairs of Mammals in Relation to the Evolution of Hairs Journal of Anatomy · 2004
    28. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    29. Trichohyalin Mechanically Strengthens the Hair Follicle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    30. Hair Loss, Insulin Resistance, and Heredity in Middle-Aged Women: A Population-Based Study European journal of cardiovascular prevention & rehabilitation · 2003
    31. Hair Biology: An Update International Journal of Cosmetic Science · 2002
    32. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    33. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    34. Early Androgenetic Alopecia as a Marker of Insulin Resistance The Lancet · 2000
    35. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998
    36. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    37. Patterned Androgenic Alopecia in Women Journal of The American Academy of Dermatology · 1988

    Related research 8

    1. Hair Loss (Alopecia or Baldness) 2018
    2. Treatments of Hereditary Hair Loss (Alopecia) 2018
    3. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
    4. Hair Disorders Associated With Anticancer Agents 2013
    5. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
    6. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    7. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    8. Treatment of Hair Loss The New England Journal of Medicine · 1999