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GlossaryEctodysplasin A Receptor

protein crucial for hair, teeth, and gland development

The Ectodysplasin A Receptor (EDAR) is a protein that plays a crucial role in the development of hair, teeth, and certain glands. Mutations in the EDAR gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases

6 citations, August 2022 in “International Journal of Molecular Sciences”

EDA signaling is linked to skin disorders, various cancers, and liver disease.

research The Biology of Hair Diversity

47 citations, January 2013 in “International Journal of Cosmetic Science”

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

207 citations, March 2012 in “Development”

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network

May 2022 in “Frontiers in Cell and Developmental Biology”

miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.

research TNF Superfamily in Skin Appendage Development

86 citations, May 2008 in “Cytokine & growth factor reviews”

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.