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    Vellus-To-Terminal Hair Follicle Reconversion Occurs In Male Pattern Balding And Is Promoted By Minoxidil And Platelet-Rich Plasma: In Vivo Evidence From A New Humanized Mouse Model Of Androgenetic Alopecia

    October 2023 in “ Acta dermato-venereologica ”
    Amos Gilhar, Aviad Keren, Ralf Paus
    Studysummary Minoxidil and platelet-rich plasma can help turn thin hair into thicker hair in male pattern baldness.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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    Research cited in this study 12

    1. Intermediate Hair Follicles from Patients with Female Pattern Hair Loss Are Associated with Nutrient Insufficiency and a Quiescent Metabolic Phenotype Nutrients · 2022
    2. Effect of Minoxidil Formulations on Human Scalp Skin Xenotransplants on SCID Mice: A Novel Pre-Clinical In Vivo Assay for Androgenetic Alopecia Research Experimental Dermatology · 2022
    3. Evidence from a Humanized Mouse Model of Androgenetic Alopecia That Platelet-Rich Plasma Stimulates Hair Regrowth, Hair Shaft Diameter, and Vellus-to-Terminal Hair Reconversion In Vivo British Journal of Dermatology · 2021
    4. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    5. Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss Using Dermal Sheath Cup Cells: A Randomized Placebo-Controlled Double-Blinded Dose-Finding Clinical Study Journal of The American Academy of Dermatology · 2020
    6. The Main Cause of Hair Rarefaction in Androgenetic Alopecia: Higher Number and Longer Duration of Kenogen Hairs Skin appendage disorders · 2018
    7. Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life The FASEB Journal · 2017
    8. Androgenetic Alopecia: Modeling Progression and Regrowth Experimental Dermatology · 2016
    9. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    10. Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth International Journal of Trichology · 2012
    11. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    12. Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women Journal of Investigative Dermatology Symposium Proceedings · 1999

    Related research 8

    1. Prognostic Factors in the Treatment of Androgenetic Alopecia with Minoxidil Медицинский совет · 2023
    2. The Cost Effectiveness of Topical Minoxidil Therapy in the Management of Baldness The FASEB Journal · 2011
    3. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    4. Australian Trial of Topical Minoxidil and Placebo in Early Male Pattern Baldness Australasian Journal of Dermatology · 1990
    5. Topical Minoxidil Does Little for Baldness Drug and Therapeutics Bulletin · 1989
    6. Quantitative Assessment of 2% Topical Minoxidil in the Treatment of Male Pattern Baldness Clinical and Experimental Dermatology · 1989
    7. Androgenetic Alopecia Treated With Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    8. 2% Topical Minoxidil Solution in Male-Pattern Baldness: Preliminary European Results Dermatology · 1987