Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells

    June 2020 in “ Nature ”
    Jiyoon Lee, Cyrus C. Rabbani, Hongyu Gao … Karl R. Koehler
    Studysummary Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on scholarworks.indianapolis.iu.edu →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach Nature Communications · 2018
    2. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018
    3. Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells Proceedings of the National Academy of Sciences of the United States of America · 2017
    4. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015
    5. Advances in Skin Grafting and Treatment of Cutaneous Wounds Science · 2014
    6. BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin PLoS Genetics · 2014
    7. Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells Nature communications · 2014
    8. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    9. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012
    10. Module-Based Complexity Formation: Periodic Patterning in Feathers and Hairs Wiley Interdisciplinary Reviews-Developmental Biology · 2012
    11. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    12. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    13. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    14. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009
    15. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008