A Systematic Review of Clinical Trials Using Single or Combination Therapy of Oral or Topical Finasteride for Women in Reproductive Age and Postmenopausal Women with Hormonal and Nonhormonal Androgenetic Alopecia

    March 2023 in “ Advances in Clinical and Experimental Medicine ”
    Niloufar Najar Nobari, Masoumeh Roohaninasab, Afsaneh Sadeghzadeh-Bazargan, Azadeh Goodarzi, Elham Behrangi, Farahnaz Nikkhah, Mohammadreza Ghassemi
    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Studysummary This systematic review concluded that 5 mg of oral finasteride per day could be an effective and safe treatment for female pattern hair loss in normoandrogenic women, particularly when combined with other medications. Our plain-language summary of this paper — not a Tressless recommendation.
    This systematic review analyzed 33 original articles on the use of oral and topical finasteride for treating female pattern hair loss (FPHL) in women of reproductive age and postmenopausal women. The review found that 5 mg of oral finasteride per day is effective and safe for normoandrogenic women with FPHL, especially when combined with other treatments like topical estradiol and minoxidil. Topical finasteride was also found to be more effective than other topical treatments for hair loss. Out of the 14 articles that met the inclusion criteria, 10 reported a high rate of alopecia recovery in women using finasteride.
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