A Systematic Review of Clinical Trials Using Single or Combination Therapy of Oral or Topical Finasteride for Women in Reproductive Age and Postmenopausal Women with Hormonal and Nonhormonal Androgenetic Alopecia

March 2023 in “ Advances in Clinical and Experimental Medicine ”

Niloufar Najar Nobari, Masoumeh Roohaninasab, Afsaneh Sadeghzadeh-Bazargan, Azadeh Goodarzi, Elham Behrangi, Farahnaz Nikkhah, Mohammadreza Ghassemi

finasteride oral finasteride topical finasteride female pattern hair loss FPHL normoandrogenic topical estradiol minoxidil androgenetic alopecia Propecia Rogaine

TLDR Oral and topical finasteride are effective and safe for treating female hair loss.

This systematic review analyzed 33 original articles on the use of oral and topical finasteride for treating female pattern hair loss (FPHL) in women of reproductive age and postmenopausal women. The review found that 5 mg of oral finasteride per day is effective and safe for normoandrogenic women with FPHL, especially when combined with other treatments like topical estradiol and minoxidil. Topical finasteride was also found to be more effective than other topical treatments for hair loss. Out of the 14 articles that met the inclusion criteria, 10 reported a high rate of alopecia recovery in women using finasteride.

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

in Progress Pictures 142 upvotes 2 years ago

A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 1 year ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community My RU58841 Progress / Hair loss journey

in Progress Pictures 69 upvotes 3 years ago

A user shared their experience with hair loss treatments, including RU58841, ketoconazole shampoo, caffeine shampoo, and topical finasteride. They found RU58841 effective for diffuse thinning but experienced severe hair loss after stopping it; topical finasteride worked well for a receding hairline but caused side effects. They also use a charcoal shampoo and practice scalp massages.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community An updated, simple guide to the most effective hair loss treatments

193 upvotes 5 years ago

Effective treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage. In addition, anti-inflammatory diets and stress management are recommended to maintain or regrow hair.

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research Ethnopharmacological Review of Medicinal Plants for the Treatment of Alopecia

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Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

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research Male Androgenetic Alopecia

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Common hair loss in men can be treated with minoxidil or finasteride.

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Minoxidil and finasteride are effective for treating hair loss, with dutasteride showing potential but with side effects.

research Androgenetic Alopecia and Its Remedies: A Review

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Topical minoxidil and oral finasteride can help regrow hair in androgenetic alopecia.

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