learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
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5 / 29 resultslearn Overview
learn Fluridil
a topical anti-androgen with less systemic involvement
learn Spironolactone
powerful topical and oral anti-androgen used mostly by women
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
Research
5 / 1000+ resultsresearch A Systematic Review of Clinical Trials Using Single or Combination Therapy of Oral or Topical Finasteride for Women in Reproductive Age and Postmenopausal Women with Hormonal and Nonhormonal Androgenetic Alopecia
Oral and topical finasteride are effective and safe for treating female hair loss.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Treatment of Androgenetic Alopecia in Females in Reproductive Age with Topical Estradiolbenzoate, Prednisolone, and Salicylic Acid
The treatment slightly increased hair growth and was safe for most women.
research Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling
Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
research Beyond Monotherapy: Adjunctive Treatments With Minoxidil for Androgenetic Alopecia
Combining minoxidil with other treatments like finasteride or PRP improves hair growth and satisfaction more than using minoxidil alone.
Community Join
5 / 1000+ resultscommunity HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)
User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.
community 4 years; fin 1mg/day @ 4 years; minox twice daily @ 3 years; estradiol 5mg/day @ 3 months; spiro 100 mg /day @ 3 months (Wet hair because it's easy to hide issues with dry hair)
The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.
community Hypothetically, if estradiol has been a "cure" for hair loss, could one apply estradiol topically and just take an estrogen blocker and/or testosterone to offset the systematic effects?
Topical estradiol may help with hair loss but can have systemic effects, like reduced testosterone production. Using estrogen blockers can have negative side effects, such as joint pain and reduced sex drive.
community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?
The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).
community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)
The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.