Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia

    Aditya K. Gupta, Milton Talukder, G. Williams
    Studysummary In this research review, the authors note that while topical minoxidil and oral finasteride are FDA-approved treatments for male androgenetic alopecia, some patients experience inadequate responses or side effects, prompting exploration of alternative therapies like newer 5-α reductase inhibitors and androgen receptor antagonists.
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    Research cited in this study 48

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    26. Efficacy and Safety of a Dietary Supplement Containing a Lipid Co-Extract from Serenoa Repens and Pygeum Africanum for the Treatment of Androgenetic Alopecia in Women: Results of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial Más dermatología · 2016
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    44. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
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    48. Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia Dermatology · 1998

    Related research 5

    1. Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review Brazilian Journal of Hair Health · 2024
    2. A Review on Finasteride: A 5-Alpha Reductase Inhibitor, Its Mechanism, Facts, and Benefits Journal of Drug Delivery and Therapeutics · 2019
    3. 5 Alpha-Reductase and Finasteride in Pattern Alopecia and Acne PubMed · 2004
    4. Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men The Journal of Clinical Endocrinology and Metabolism · 1996
    5. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992