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5α-Reductase Inhibitors and Male Reproduction

research 5α-Reductase Inhibitors (5ARIs) and Male Reproduction

15 citations , January 2017 in “Advances in Experimental Medicine and Biology”

This review discusses the effects of 5ARI drugs on male reproductive parameters, reporting potential decreases in sperm count and motility more significantly in men with pre-existing oligozoospermia, but does not provide fertility outcomes.

research PCPT, MTOPS and the use of 5ARIs: a Canadian consensus regarding implications for clinical practice

13 citations , December 2012 in “Canadian Urological Association Journal”

This report from a consensus meeting concluded that while 5-alpha reductase inhibitors are beneficial for BPH treatment and prostate cancer risk reduction, their role in clinical practice should be more widely integrated into prostate management guidelines.

research The Risk of Venous Thromboembolism (VTE) in Men with Benign Prostatic Hyperplasia Treated with 5-Alpha Reductase Inhibitors (5ARIs).

6 citations , August 2021 in “Clinical Epidemiology”

Men using 5-alpha reductase inhibitors for prostate issues may have a slightly higher risk of blood clots.

research 5ARIs and PSA: Evidences

3 citations , May 2014 in “Urologia Journal”

This review discusses how 5α-reductase inhibitors affect PSA levels in benign prostatic hyperplasia treatment and their role in prostate cancer screening, but reports no new clinical findings.

Comments Concerning the Real Risk of Sexual Adverse Events Secondary to the Use of 5-Alpha-Reductase Inhibitors

research Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs

January 2016 in “Archivio italiano di urologia, andrologia”

This article reviews treatment-induced sexual dysfunctions related to 5-alpha-reductase inhibitors and reports no new results; it highlights the need to better define and understand this controversial topic.

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Community Join

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community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

37 upvotes 3 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Second shed !! min 5% fin 1mg 28M

in Is this regrowth? 15 upvotes 4 months ago

Users are experiencing hair shedding after initial improvement using treatments like Minoxidil, finasteride, and dutasteride. Shedding is seen as a sign of progress, but concerns arise when hair falls out again after a few months.

community 6,5 months update. What do you think?

in Minoxidil 121 upvotes 1 year ago

The user is using 5 mg of oral minoxidil, 1.25 mg of finasteride, and a dermaroller for hair loss, and plans to reduce the minoxidil dosage after a year. They have not experienced side effects like facial bloating and are considering the safety of long-term use.

community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes

1023 upvotes 1 year ago

The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.

community [AMA] 5-Month Progress Report: Dutasteride and Oral Minoxidil Results.

73 upvotes 5 years ago

Naepo's 5-month progress report detailing their journey of treating male pattern baldness with dutasteride and oral minoxidil, which has already resulted in an encouraging improvement in hair density. Others have responded with appreciation for the thorough report and asked further questions about Naepo's educational background.

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Experts

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Biopeptide-5

learn O-Cymen-5-Ol

learn Minoxidil

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.

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