The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology

    January 2024 in “ Skin appendage disorders ”
    Tara Samra, Rachel Lin, Andrea D. Maderal
    Studysummary This research highlights that various environmental pollutants, including particulate matter, tobacco smoke, and heavy metals, can significantly affect hair follicle health, linking them to conditions like alopecia areata and androgenetic alopecia, underscoring the need for further study in this area.
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    Research cited in this study 26

    1. Environmental Pathobiology of Frontal Fibrosing Alopecia: A Link Between Linalool Sensitization and FFA Development Journal of Investigative Dermatology · 2023
    2. Human Occupational Exposure to Microplastics: A Cross-Sectional Study in a Plastic Products Manufacturing Plant Science of The Total Environment · 2023
    3. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    4. Role of Smoking in Androgenetic Alopecia: A Systematic Review International Journal of Trichology · 2022
    5. Human Hair Follicles Operate an Internal Cori Cycle and Modulate Their Growth via Glycogen Phosphorylase Scientific Reports · 2021
    6. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    7. The Epidemiology of Alopecia Areata: A Population-Based Cohort Study in UK Primary Care British Journal of Dermatology · 2021
    8. The Impact of Air Pollution on Skin and Related Disorders: A Comprehensive Review Dermatologic Therapy · 2021
    9. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    10. Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters Journal of Cosmetic Dermatology · 2020
    11. Patch Testing and Contact Allergen Avoidance in Patients with Lichen Planopilaris and/or Frontal Fibrosing Alopecia: A Cohort Study Journal of the American Academy of Dermatology · 2020
    12. Alopecia Areata and Toxic Metals Skin appendage disorders · 2020
    13. Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine International Journal of Cosmetic Science · 2019
    14. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    15. Alopecia and Associated Toxic Agents: A Systematic Review Skin appendage disorders · 2018
    16. Aryl Hydrocarbon Receptor Overexpression in Miniaturized Follicles in Female Pattern Hair Loss Anais Brasileiros De Dermatologia · 2017
    17. A New Path in Defining Light Parameters for Hair Growth: Discovery and Modulation of Photoreceptors in Human Hair Follicle Lasers in surgery and medicine · 2017
    18. Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix European Journal of Cell Biology · 2017
    19. Effect of Alpha Lipoic Acid on Smoking-Induced Skin Damage Cutaneous and ocular toxicology · 2016
    20. Oxidative Modification in Human Hair: The Effect of the Levels of Cu (II) Ions, UV Exposure and Hair Pigmentation Photochemistry and photobiology · 2015
    21. Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair Current problems in dermatology · 2015
    22. Hair Follicles Contribute Significantly to Penetration Through Human Skin Only Shortly After Application as a Solvent Deposited Solid in Humans BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2011
    23. The Role of Hair Follicles in the Percutaneous Absorption of Caffeine BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2007
    24. Is Androgenetic Alopecia a Photoaggravated Dermatosis? Dermatology · 2003
    25. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    26. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996