TLDR Lifestyle changes and environmental strategies can help address declining testosterone levels.
The article examines the secular decline in testosterone levels, attributing it to factors like obesity, sedentary lifestyle, poor diet, inadequate sleep, stress, and exposure to endocrine disruptors. This decline is linked to health issues such as reduced fertility, metabolic and cardiovascular diseases, psychological effects, and musculoskeletal problems. Interventions to address this decline include lifestyle changes like weight loss, exercise, balanced diet, and stress management, alongside pharmacological options like testosterone replacement therapy. The article highlights evidence from studies, including a global analysis of over 1 million subjects, indicating a significant annual decline in testosterone levels.
60 citations
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January 2023 in “Biogerontology” Adequate testosterone is crucial for men's health and quality of life, but its decline with age needs more research.
49 citations
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November 2019 in “Egyptian Journal of Medical Human Genetics” Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
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January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Acne is an important sign of androgen excess disorders in women.
70 citations
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March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
186 citations
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February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
305 citations
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February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
207 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.