Genome-Wide Association Study Identifies a New Locus JMJD1C at 10q21 That May Influence Serum Androgen Levels in Men

A user on Finasteride for 7-8 years reported unexpectedly high testosterone levels despite expecting lower levels due to age, with discussions on the impact of SHBG and suggestions to use boron to lower SHBG. Another user noted that Dutasteride significantly increased their testosterone and free testosterone levels.

The conversation is about gathering serum DHT data from individuals taking dutasteride to investigate its efficacy, especially in cases with unexpectedly low DHT reduction. The aim is to explore potential genetic factors affecting drug metabolism.

The user received hormone test results showing normal estradiol and testosterone levels, low SHBG, and normal free androgen index. They are considering starting finasteride but are concerned due to being slightly overweight.

The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.

A user discusses their hormone blood test results before starting finasteride for hair loss, noting high DHT and estradiol levels. They tried topical finasteride for a few days but felt tired.

The user is taking finasteride and minoxidil for hair loss, but their DHT levels are unusually high, leading to suspicion of lab errors. They plan to retest at a different lab to confirm results.