TLDR Adequate testosterone is crucial for men's health and quality of life, but its decline with age needs more research.
The document discusses the importance of adequate testosterone levels for male health, quality of life, and longevity. Testosterone influences various body systems, including skeletal, muscle, adipose tissues, and the cardiovascular, immune, and nervous systems. It also examines the effects of diseases, aging, nutrition, and the environment on testosterone levels. As men age, testosterone levels naturally decline, but the precise mechanisms and health impacts of this decline are not fully understood. Further research is necessary to identify optimal testosterone levels to prevent age-related conditions like frailty and osteoporosis.
23 citations
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January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
21 citations
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January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
22 citations
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October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
35 citations
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January 2018 in “Vitamins and hormones” DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.
50 citations
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February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
101 citations
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April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
