Alternatives/unorthodox hairloss protocols to the big three
    Chat 1/17/2026

    At a glance
    In this general discussion post, the primary subjects mentioned are
    Dutasteride 5 years
    💧 RU58841 (topical)
    💊 Nandrolone (oral)
    💊 Dianabol (oral) 2-3mg daily daily
    💊 Estrogen (oral) extreme doses
    the tone is 😐 neutral.
    The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.
    View this post in the Community →

    Similar Community Posts Join

    6 / 1000+ results

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Nandrolone Replacement Therapy

      in Treatment  44 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 1 year ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community Pyrilutamide - your experience?

      in Product  12 upvotes 3 years ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community My Pyrilutamide Experience so far

      in Update  78 upvotes 3 years ago
      A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

    Related Research

    6 / 1000+ results
      Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      November 2020 in “Elsevier eBooks”
      Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
      Androgenetic Alopecia: Pathogenetic Mechanisms and Treatment Approaches

      research Androgenetic Alopecia: Pathogenetic Mechanisms and Treatment Approaches

      January 2013 in “Российский журнал кожных и венерических болезней”
      Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.