Steroid Hormones of Reproduction and Sexual Development

    January 2017 in “ Elsevier eBooks ”
    Angelo Mariotti
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    TLDR Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
    The document from 2017 examines the effects of sex steroid hormones—estrogens, progestins, and androgens—on reproduction, sexual development, and oral tissues. It outlines the physiological roles of these hormones and their pharmacological uses, such as in contraception, menopausal therapy, and cancer treatment. The document also discusses the side effects and interactions of these hormones, including increased risks of thromboembolic disorders with estrogen therapy and blood clots with progestins. It notes that low-dose oral contraceptives do not increase gingival disease levels, but non-compliance or multiple dosages could raise the risk of estrogen-induced pyogenic granuloma. The importance of dental practitioners understanding the biological responses to these hormones, drug interactions, and their potential effects on dental materials is emphasized. The document includes a case study illustrating the clinical relevance of hormone knowledge in diagnosis and treatment, and lists various medications related to reproductive hormones.
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