TLDR Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
The review explores the effects of hormone therapy on the reproductive health and overall well-being of transgender individuals, highlighting significant mental health benefits and the complex interplay between hormones, circadian rhythms, and fertility. It underscores the importance of monitoring potential risks, such as impacts on bone and cardiovascular health, and emphasizes the need for fertility preservation options. The review calls for further research on the long-term effects of hormone therapy and stresses the critical role of healthcare providers in delivering affirming care, aiming to inform healthcare providers, policymakers, and transgender individuals to guide decision-making and improve care quality.
Cited in this study
6 / 6 results
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
162 citations
,
April 2017 in “The Lancet Diabetes & Endocrinology” Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
146 citations
,
December 2016 in “Translational Andrology and Urology” Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
204 citations
,
August 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
29 citations
,
May 2013 in “Andrologia” Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.
2295 citations
,
August 2012 in “The international journal of transgenderism/International journal of transgenderism” The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.
1 citations
,
October 2022 in “Adolescent Health, Medicine and Therapeutics” Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
