Alopecia and Associated Toxic Agents: A Systematic Review

    January 2018 in “ Skin appendage disorders
    Vicky Yu, Margit Juhász, Audris Chiang, Natasha Atanaskova Mesinkovska
    TLDR Thallium, mercury, selenium, and colchicine strongly cause hair loss.
    The systematic review "Alopecia and Associated Toxic Agents" examined the relationship between various toxic agents and alopecia, identifying 47 relevant studies from an initial pool of 856 articles. It found strong evidence linking thallium, mercury, selenium, and colchicine to hair loss, with other agents like boric acid, arsenic, vitamin A, botulinum toxin, Podostroma cornu-damae, and synthetic opioids like MT-45 also implicated but with less robust evidence. The review highlighted the importance of recognizing these toxic agents in clinical settings to aid in differential diagnosis and emphasized the need for further research into less well-documented toxins.
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