Skin Signs in the Diagnosis of Thallium Poisoning

    February 1998 in “ British Journal of Dermatology
    Tromme, Van Neste, Dobbelaere, Bouffioux, Courtin, Dugernier, Pierre, Dupuis
    TLDR Thallium poisoning can cause severe neurological symptoms and hair loss.
    The document described a case of a 45-year-old man who developed severe neurological symptoms, including sensory-motor polyneuropathy, confusion, and convulsions, leading to respiratory failure and coma. After 3 weeks in intensive care, he experienced rapid and diffuse hair loss (alopecia). Examination of his hair roots revealed dystrophic anagen hairs with dark bands, a characteristic sign of thallium poisoning. A toxicological investigation confirmed thallium exposure. The study reviewed the systemic symptoms, dermatological signs, and discussed the origins and physiopathology of thallium contamination.
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