Alfatradiol!!! Does anyone use this as part of their stack and can actually comment on its effectiveness?
    4/7/2025

    From the encyclopedia
    Alfatradiol β†’

    a synthetic estrogen used topically as an anti-androgen

    Finasteride β†’

    Frontline, gold standard treatment for combatting androgenic alopecia

    RU58841 β†’

    a potent but unapproved and potentially problematic topical anti-androgen

    At a glance
    In this question or advice post, the primary subjects mentioned are
    πŸ’§ Alfatradiol (topical) more than 6 months
    β€’ RU58841
    β€’ Minoxidil
    the tone is 😐 neutral with unclear results.

    Other terms

    Alfatradiol is used by some for hair loss, often alongside treatments like finasteride, RU58841, and minoxidil, but its effectiveness is unclear. Some users report no significant improvement, while others note reduced sebum production but experience side effects like gallbladder pain.
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    5 / 5 results

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

       124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Switch from fin to dut and its worse

       4 upvotes 1 year ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

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