Effects of Platelet-Rich Plasma on In Vitro Hair Follicle Germ Preparation for Hair Regenerative Medicine

    Tatsuto Kageyama, Ayaka Nanmo, Lei Yan, Tadashi Nittami, Junji Fukuda
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    TLDR Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
    Three years ago, a study was conducted to examine the impact of platelet-rich plasma releasate (PRPr) on the development and hair growth activity of hair follicle germs (HFGs). The research found that PRPr did not obstruct the formation of HFGs and actually increased follicular gene expression. Additionally, the hair regeneration ability was significantly improved with PRPr. Three key growth factors in PRPr - platelet-derived growth factor (PDGF), fibroblast growth factor-2 (FGF2), and vascular endothelial growth factor (VEGF) - were identified as contributing to this improvement. The study concluded that PRPr, which can be obtained from the patient's own blood, could potentially enhance the efficiency of hair regeneration in clinical applications.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 weeks ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 7 months ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  14 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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