Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated With p16INK4a Expression

November 2007 in “ Journal of Investigative Dermatology ”

Adiam W. Bahta, Nilofer Farjo, Bessam Farjo, Michael P. Philpott

androgenetic alopecia dermal papilla cells p16INK4a oxidative stress DNA damage heat shock protein-27 AGA DPC

Studysummary This study found that balding dermal papilla cells show premature senescence and altered expression of stress and DNA damage markers, suggesting sensitivity to environmental stress in androgenetic alopecia.

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