TLDR The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.
This document from 1988 reports the discovery of a mutation in a mouse colony that leads to androgen-dependent alopecia, which is similar to male pattern baldness in humans. The study suggests that this mouse model could serve as an alternative to the stumptailed macaque, which was previously used for hair loss research but is limited by availability and maintenance costs. The mouse model could be valuable for studying the mechanisms of baldness and for testing potential therapeutic compounds, such as testosterone, cyproterone acetate, and minoxidil. The document does not provide specific data on the number of mice studied or the effects of the mentioned compounds on hair loss.
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18 citations
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April 1986 in “International Journal of Cosmetic Science” Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
June 2022 in “South Florida Journal of Health”
June 2018 Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
30 citations
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June 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
August 2014 in “Journal of drug discovery and therapeutics”
January 2014 in “American Journal of Medicine and Medical Sciences” Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.
January 2009 in “Revista de Ciências Médicas” Male pattern baldness is a genetic condition causing hair loss, with limited but improving treatment options.
12 citations
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October 1988 in “Clinics in dermatology” The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.