The Effect of Testosterone, Cyproterone Acetate, and Minoxidil on Hair Loss in Androgenetic Alopecia Mouse

    October 1988 in “ Clinics in dermatology ”
    Jonathan R. Matias, Norman Orentreich
    TLDR The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.
    This document from 1988 reports the discovery of a mutation in a mouse colony that leads to androgen-dependent alopecia, which is similar to male pattern baldness in humans. The study suggests that this mouse model could serve as an alternative to the stumptailed macaque, which was previously used for hair loss research but is limited by availability and maintenance costs. The mouse model could be valuable for studying the mechanisms of baldness and for testing potential therapeutic compounds, such as testosterone, cyproterone acetate, and minoxidil. The document does not provide specific data on the number of mice studied or the effects of the mentioned compounds on hair loss.
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      community It’s over. NOTHING has worked.

      in Chat  95 upvotes 1 year ago
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      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  123 upvotes 11 months ago
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      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  56 upvotes 1 year ago
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      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  35 upvotes 1 year ago
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