Recent Trends in Macromolecule-Based Approaches for Hair Loss Treatment

May 2023 in “ Macromolecular Bioscience ”

Moon Sung Kang, Tae Eon Park, Hyo Jung Jo, Min Seok Kang, Su Bin Lee, Suck Won Hong, Ki Su Kim, Dong‐Wook Han

macromolecules hair regeneration therapies hair follicle morphogenesis hair shaft development hair cycle regulation alopecia microneedles nanoparticles tissue-engineered scaffolds hair follicle neogenesis in vitro in vivo artificial skin platforms

TLDR Macromolecules show promise for future hair loss treatments.

The review discusses recent advancements in using macromolecules for hair loss treatment, highlighting their potential in hair regeneration therapies. It covers the fundamental principles of hair follicle morphogenesis, hair shaft development, hair cycle regulation, and alopecia. Innovative delivery systems like microneedles and nanoparticles are explored, along with macromolecule-based tissue-engineered scaffolds for hair follicle neogenesis both in vitro and in vivo. Additionally, the review introduces artificial skin platforms as a promising method for screening hair loss treatment drugs. These approaches underscore the potential of macromolecules in developing future hair loss treatments. The authors report no conflicts of interest.

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