Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia

November 2019 in “ Journal of Controlled Release ”

Suyong Kim, Jaehong Eum, Huisuk Yang, Hyungil Jung

transdermal delivery finasteride androgenetic alopecia microneedles diffusion enhancer Propecia

TLDR Microneedles with enhancer effectively promote hair growth and increase hair density.

The study aimed to develop a transdermal delivery system for finasteride to treat androgenetic alopecia using powder-carrying microneedles with a diffusion enhancer. The system showed a higher efficacy in promoting hair growth and increased the amount and density of hair while addressing safety concerns. The study demonstrated the potential of the system as a transdermal delivery system for finasteride to treat androgenetic alopecia.

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Research cited in this study

16 / 16 results

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Combining MSM with MAP significantly promotes hair growth.

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Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

research Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes

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Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Simultaneous Effects of Tocopheryl Polyethylene Glycol Succinate on Local Hair Growth Promotion and Systemic Absorption of Topically Applied Minoxidil in a Mouse Model

research Simultaneous Effects of Tocopheryl Polyethylene Glycol Succinate on Local Hair Growth Promotion and Systemic Absorption of Topically Applied Minoxidil in a Mouse Model

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Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.

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112 citations, October 2005 in “Mayo Clinic Proceedings”

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

research Finasteride in the Treatment of Androgenetic Alopecia

62 citations, April 2004 in “Expert Opinion on Pharmacotherapy”

Finasteride effectively treats male pattern baldness, improving hair growth and density.

research Minoxidil vs Finasteride in the Treatment of Men With Androgenetic Alopecia

40 citations, September 2003 in “Archives of Dermatology”

Finasteride slightly better long-term, minoxidil faster initial results, but stopping minoxidil may cause hair loss.

research Androgenetic Alopecia: Pathogenesis and Potential for Therapy

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Hair loss needs more research for better treatments.

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Treatments for Androgenetic Alopecia and Alopecia Areata