Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia

December 2019 in “ Journal of Controlled Release ”

Suyong Kim, Jaehong Eum, Huisuk Yang, Hyungil Jung

transdermal delivery finasteride androgenetic alopecia microneedles diffusion enhancer Propecia

TLDR Microneedles with enhancer effectively promote hair growth and increase hair density.

The study aimed to develop a transdermal delivery system for finasteride to treat androgenetic alopecia using powder-carrying microneedles with a diffusion enhancer. The system showed a higher efficacy in promoting hair growth and increased the amount and density of hair while addressing safety concerns. The study demonstrated the potential of the system as a transdermal delivery system for finasteride to treat androgenetic alopecia.

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16 / 16 results

research Microneedling for the Treatment of Hair Loss

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research Alopecia: Evaluation and Treatment

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research Enhancement of Percutaneous Absorption of Finasteride by Cosolvents, Cosurfactant, and Surfactants

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research The Effect of Methylsulfonylmethane on Hair Growth Promotion of Magnesium Ascorbyl Phosphate for the Treatment of Alopecia

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research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation

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Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

research Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes

127 citations , October 2006 in “International Journal of Pharmaceutics”

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

research Simultaneous Effects of Tocopheryl Polyethylene Glycol Succinate on Local Hair Growth Promotion and Systemic Absorption of Topically Applied Minoxidil in a Mouse Model

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research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men

112 citations , October 2005 in “Mayo Clinic Proceedings”

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62 citations , April 2004 in “Expert Opinion on Pharmacotherapy”

Finasteride effectively treats male pattern baldness, improving hair growth and density.

research Minoxidil vs Finasteride in the Treatment of Men With Androgenetic Alopecia

40 citations , September 2003 in “Archives of Dermatology”

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research Finasteride

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10 / 10 results

research Hair Loss in Lichen Planopilaris and Frontal Fibrosing Alopecia: Not Always Irreversible

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research Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia

33 citations , December 2019 in “Journal of Controlled Release”

Microneedles with enhancer effectively promote hair growth and increase hair density.

research Transdermal Delivery of a New Hair Growth Promoting Solution in Patients with Hair Loss

2 citations , January 2019 in “International Journal of Case Reports and Images”

The hair growth solution reduced hair loss and increased hair thickness in a small group of patients.

research Frontal Fibrosing Alopecia Treatment Options

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research Finasteride in the Treatment of Female Androgenic Alopecia

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research Androgens and Alopecia

165 citations , December 2002 in “Molecular and Cellular Endocrinology”

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.