Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

    January 2018 in “ Pharmaceutics ”
    Eman Abd, Heather A. E. Benson, Michael S. Roberts, Jeffrey E. Grice
    Image of study
    TLDR Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
    A study from 5 years ago found that nanoemulsion formulations containing eucalyptol or oleic acid can improve the delivery of minoxidil to hair follicles, potentially enhancing its effectiveness in treating hair loss. Eucalyptol retained minoxidil in deeper skin layers, while oleic acid had the greatest hair follicle penetration. The study aimed to improve the delivery of minoxidil to hair follicles by developing and testing nanoemulsion formulations containing eucalyptol or oleic acid. The formulations were clear and contained surfactant, co-surfactant, and phosphate buffered saline. Minoxidil was dissolved in the nanoemulsion and control solutions. However, further research is needed to confirm these findings in vivo.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 1000+ results

      community How to deal with mechanically induced shedding

      in Minoxidil  4 upvotes 2 months ago
      Minoxidil can cause scalp dryness and flaking, leading to hair shedding when exfoliating. Alternatives like oral Minoxidil, finasteride, and ketoconazole shampoo are suggested to manage these issues.

      community Minoxidil causes eye issues as per this article

      in Minoxidil 3 days ago
      Minoxidil is discussed as a hair loss treatment, with concerns about potential eye issues. Some users express skepticism about these claims, while others emphasize the long-standing use of Minoxidil.

      community 1 Month RU58841 + Minoxidil + Weekly microneedle

      in Minoxidil  1 upvotes 4 days ago
      The user is using RU58841, Minoxidil, and weekly microneedling for hair loss, having stopped finasteride due to side effects like low libido and depression. They are considering dutasteride as an alternative but are cautious due to past experiences with DHT blockers.

      community “Just minoxidil” users, how are you doing now?

      in Minoxidil  24 upvotes 4 days ago
      Minoxidil alone is often insufficient for significant hair regrowth, with many users experiencing limited results or side effects, leading them to add finasteride or dutasteride for better outcomes. Some users report initial improvements with minoxidil but eventually require additional treatments to maintain or enhance hair growth.

      community Topical minoxidil responder tests + switching to oral

      in Minoxidil  1 upvotes 4 days ago
      The user has been using topical minoxidil with tretinoin for 9 months without much regrowth and suspects finasteride is responsible for any improvement. They are inquiring about tests to determine response to topical minoxidil and seeking advice on switching to oral minoxidil, including potential side effects and monitoring requirements.

    Related Research

    3 / 3 results