Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions

    February 2009 in “ European journal of pharmaceutics and biopharmaceutics ”
    Jürgen Lademann, Alexa Patzelt, Heike Richter … Martina C. Meinke
    Studysummary This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.
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    Research cited in this study 7

    1. The Role of Hair Follicles in the Percutaneous Absorption of Caffeine BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2007
    2. Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream European journal of pharmaceutics and biopharmaceutics · 2007
    3. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007
    4. Bulge Cells of Human Hair Follicles: Segregation, Cultivation, and Properties Colloids and Surfaces B: Biointerfaces · 2006
    5. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    6. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    7. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005