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Glossary Porcine Ear Skin

skin tissue from pig ears used in dermatological research

Porcine Ear Skin, also known as Pig Ear Skin, refers to the skin tissue from the ears of pigs. It is commonly used in scientific research and dermatological studies because its structure and properties closely resemble human skin. This makes it a valuable model for testing the effects of various treatments, studying skin diseases, and evaluating the penetration of topical medications.

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research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin

18 citations , October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics”

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin

15 citations , October 2020 in “European journal of pharmaceutics and biopharmaceutics”

This study reported that combining microdialysis and selective follicular closure with varnish significantly reduces caffeine penetration through hair follicles in an ex vivo porcine ear skin model.

research Solvent-Containing Closure Material Can Be Used to Prevent Follicular Penetration of Caffeine and Fluorescein Sodium Salt on Porcine Ear Skin

7 citations , January 2020 in “Skin Pharmacology and Physiology”

In this study using ex vivo porcine ear skin, researchers found that standard nail varnish applied gently creates effective follicular closures, preventing penetration of certain substances like fluorescein sodium salt and caffeine into hair follicles, whereas solvent-free varnish and rapid application techniques were less effective.

research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument

January 2011

In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.

research In vitroinvestigation of the follicular penetration of porcine ear skin using a nanoparticle-emulsion containing the antiseptic polihexanide

8 citations , April 2012 in “Laser Physics Letters”

This study found that a curcumin-labeled particle-associated antiseptic penetrated deeper into hair follicles in porcine skin than particles without antiseptic.

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