Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules

    Hye-Ji Lee, Ha-Kyoung Kwon, Hye Su Kim … Hye-Jin Park
    Studysummary This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 41

    1. Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways International Journal of Molecular Sciences · 2018
    2. Nanotechnology Advances for Hair Loss Therapeutic Delivery · 2018
    3. Undariopsis Peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways Marine Drugs · 2017
    4. Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells Journal of Cosmetic Dermatology · 2017
    5. Changing the Shape of Hair with Keratin Peptides RSC Advances · 2017
    6. Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia Molecular and Cellular Endocrinology · 2016
    7. Glycyrrhizic Acid Attenuates Stem Cell-Like Phenotypes of Human Dermal Papilla Cells Phytomedicine · 2015
    8. Regulation Mechanisms of Hair Growth Current problems in dermatology · 2015
    9. In Vivo Hair Growth Promotion Effects of Ultra-High Molecular Weight Poly-γ-Glutamic Acid from Bacillus Subtilis (Chungkookjang) Journal of Microbiology and Biotechnology · 2015
    10. Keratins: The Hair Shaft's Backbone Revealed Experimental Dermatology · 2015
    11. Hair Growth Promotion Activity and Its Mechanism of Polygonum Multiflorum Evidence-based Complementary and Alternative Medicine · 2015
    12. Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration World Journal of Stem Cells · 2015
    13. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    14. CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis Journal of Dietary Supplements · 2014
    15. Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis BMC Complementary and Alternative Medicine · 2013
    16. Damage of Hair Follicle Stem Cells and Alteration of Keratin Expression in External Radiation-Induced Acute Alopecia International Journal of Molecular Medicine · 2012
    17. Topical Application of Polygonum Multiflorum Extract Induces Hair Growth of Resting Hair Follicles Through Upregulating Shh and β-Catenin Expression in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    18. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    19. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    20. Nutritional Clinical Studies in Dermatology Springer eBooks · 2011
    21. Keratin Gene Mutations in Disorders of Human Skin and Its Appendages Archives of Biochemistry and Biophysics · 2010
    22. Hair Loss in Long-Term or Home Parenteral Nutrition: Are Micronutrient Deficiencies to Blame? Current Opinion in Clinical Nutrition & Metabolic Care · 2010
    23. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    24. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    25. Hair Follicular Cell/Organ Culture in Tissue Engineering and Regenerative Medicine Biochemical Engineering Journal · 2009
    26. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    27. Eclipta Alba Extract With Potential For Hair Growth Promoting Activity Journal of Ethnopharmacology · 2009
    28. Expression Patterns of Keratin Intermediate Filament and Keratin Associated Protein Genes in Wool Follicles Differentiation · 2009
    29. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    30. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    31. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    32. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    33. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    34. Dermal Papilla-Induced Hair Differentiation of Adult Epithelial Stem Cells from Human Skin Physiological Genomics · 2004
    35. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    36. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003
    37. Cyclic Alopecia in Msx2 Mutants: Defects in Hair Cycling and Hair Shaft Differentiation Development · 2002
    38. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002
    39. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    40. Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance Dermatologic clinics · 1996
    41. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993