Clinical And Preclinical Approach In AGA Treatment: A Review Of Current And New Therapies In The Regenerative Field

August 2024 in “ Stem Cell Research & Therapy ”

Lorena Pozo-Pérez, Pilar Tornero-Esteban, Eduardo López-Bran

androgenetic alopecia AGA platelet-rich plasma platelet-rich fibrin hair follicle stem cells mesenchymal stem cell-based treatments conditioned medium exosomes nanotechnology bioinks nanobiomaterials 3D bioprinting PRP PRF stem cell therapy

TLDR New regenerative therapies show promise for treating hair loss.

The review discusses current and emerging therapies for androgenetic alopecia (AGA), highlighting the limitations of existing treatments like Minoxidil and Finasteride due to adverse effects and diminishing long-term efficacy. It explores the potential of regenerative approaches, including the use of autologous and allogenic stem cells, exosomes, and advanced 3D bioprinting techniques. These methods aim to restore the hair follicle's microenvironment or create new hair follicles. Clinical studies show promising results, but further research is needed to standardize protocols and optimize biomaterials for effective and safe application in AGA treatment.

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117 citations , September 2013 in “Lasers in Surgery and Medicine”

Red light therapy at 655 nm significantly improved hair growth in men with hair loss.

Related Research

5 / 5 results

research Hair Loss

August 2021 in “Pharmacy Today”

The document's conclusion about hair loss cannot be determined.

research Diffuse Hair Loss

June 2021 in “Elsevier eBooks”

The document's conclusion cannot be summarized because it is not readable or understandable.

research A Review on Hair Loss and Damage

January 2016

The article concludes that understanding the causes of hair loss and using continuous treatments like minoxidil and finasteride can help manage it, despite potential side effects.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Towards a Molecular Understanding of Hair Loss and Its Treatment

236 citations , July 2001 in “Trends in Molecular Medicine”

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.