Image

    Hormones and Clocks: Do They Disrupt the Locks? Fluctuating Estrogen Levels During Menopausal Transition May Influence Clock Genes and Trigger Chronic Telogen Effluvium

    May 2016 in “ Dermatology Online Journal
    Paradi Mirmirani
    Studysummary This review discusses chronic telogen effluvium, focusing on the potential role of hormonal fluctuations and circadian control genes, and reports no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on escholarship.org →
    Discuss this study in the Community →

    Research cited in this study 31

    1. Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle PLoS ONE · 2015
    2. Chronic Telogen Effluvium and Female Pattern Hair Loss Are Separate and Distinct Forms of Alopecia: A Histomorphometric and Immunohistochemical Analysis Clinical and Experimental Dermatology · 2014
    3. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013
    4. Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen PLOS ONE · 2012
    5. What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women British Journal of Dermatology · 2012
    6. Noninvasive Method for Assessing the Human Circadian Clock Using Hair Follicle Cells Proceedings of the National Academy of Sciences of the United States of America · 2010
    7. Chronic Telogen Effluvium Is Due to a Reduction in the Variance of Anagen Duration Australasian Journal of Dermatology · 2010
    8. Clock Genes, Hair Growth, and Aging Aging · 2010
    9. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006
    10. Physiological and Biological Skin Changes in Pregnancy Clinics in Dermatology · 2006
    11. Substantial Sex-Dependent Differences in the Response of Human Scalp Hair Follicles to Estrogen Stimulation In Vitro Advocate Gender-Tailored Management of Female Versus Male Pattern Balding Journal of Investigative Dermatology Symposium Proceedings · 2005
    12. Estrogen Functions in Skin and Skin Appendages Expert Opinion on Therapeutic Targets · 2005
    13. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor Alpha Is Checked by ER Beta Signaling Endocrinology · 2005
    14. Chronic Telogen Effluvium: A Study of 5 Patients Over 7 Years Journal of The American Academy of Dermatology · 2005
    15. The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women Journal of The American Academy of Dermatology · 2004
    16. Estrogens And The Hair Follicle Journal der Deutschen Dermatologischen Gesellschaft · 2004
    17. Estrogens and Human Scalp Hair Growth: More Questions Than Answers Journal of Investigative Dermatology · 2004
    18. Topical Estrogen Accelerates Hair Regrowth in Mice After Chemotherapy-Induced Alopecia by Favoring the Dystrophic Catagen Response Pathway to Damage Journal of Investigative Dermatology · 2004
    19. Scalp Hair Diameter Increases During Pregnancy Clinical and Experimental Dermatology · 2003
    20. The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit Journal of Investigative Dermatology Symposium Proceedings · 2003
    21. Estrogen Receptor Alpha, But Not Estrogen Receptor Beta, Is Involved in the Regulation of Hair Follicle Cycling and Epidermis Thickness in Male Mice Journal of Investigative Dermatology · 2002
    22. Chronic Telogen Effluvium in a Man Journal of The American Academy of Dermatology · 2002
    23. 17β-Estradiol and ICI-182780 Regulate the Hair Follicle Cycle in Mice Through an Estrogen Receptor-α Pathway Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism · 2000
    24. Chronic Telogen Effluvium: Incidence, Clinical and Biochemical Features, and Treatment Archives of Dermatology · 1999
    25. On The Effect Of Estrogen Receptor Agonists And Antagonists On The Mouse Hair Follicle Cycle Journal of Investigative Dermatology · 1998
    26. Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling Journal of Investigative Dermatology · 1998
    27. Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women Journal of The American Academy of Dermatology · 1996
    28. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    29. Chronic Telogen Effluvium Dermatologic Clinics · 1996
    30. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993
    31. Pathologic Dynamics of Human Hair Loss Archives of Dermatology · 1961

    Related research 8

    1. Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp Journal of Cosmetic Dermatology · 2022
    2. Efficacy and Safety of a Botanical Topical Serum on Male and Female Androgenetic Alopecia Journal of Cosmetics, Dermatological Sciences and Applications · 2022
    3. Autologous Whole Fat Injection Stimulates Hair Growth in Resistant Androgenetic Alopecia: Report of Nine Cases Journal of Cosmetic Dermatology · 2020
    4. A Pilot Evaluation of Scalp Skin Wounding to Promote Hair Growth in Female Pattern Hair Loss International Journal of Women's Dermatology · 2020
    5. Hair Loss (Alopecia or Baldness) 2018
    6. Treatments of Hereditary Hair Loss (Alopecia) 2018
    7. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    8. Nonscarring Hair Loss Disorders Postgraduate Medicine · 1982