Chronic Telogen Effluvium and Female Pattern Hair Loss Are Separate and Distinct Forms of Alopecia: A Histomorphometric and Immunohistochemical Analysis

    Carla Bittencourt, D. A. Ferraro, Taís Cristina Bastos Soares, Arthur Moraes, Maria Letícia Cintra
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    TLDR CTE and FPHL are different hair loss types with unique causes.
    The study aimed to differentiate between chronic telogen effluvium (CTE) and female pattern hair loss (FPHL) through histomorphometric and immunohistochemical analysis. The results showed that CTE is a distinct disorder from FPHL, with different pathogenic mechanisms. CTE is related to immediate telogen release, leading to cycle synchronization, while FPHL is related to accelerated anagen follicular mitotic rates, resulting in hair miniaturization. The study adds to the understanding of the pathogenesis of these conditions, which is important for therapeutic tests.
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