Frontal Edema Due to Mesotherapy for Androgenetic Alopecia: A Case Series

    December 2021 in “ Dermatologic Therapy
    Daniel Melo, David Saceda-Corralo, Antonella Tosti, Francisco C. Weffort, Machado Carla Jorge, Claudia Franca Barros, Raquel Carvalho, Michela Starace
    TLDR Mesotherapy for hair loss can cause temporary forehead swelling.
    This multicenter retrospective study reports 14 cases of frontal edema resulting from mesotherapy for androgenetic alopecia (AGA) treatment. The edema typically appeared within the first two sessions and lasted between 1 and 4 days, resolving favorably with local cold compresses. Lidocaine was used as the anesthetic in all cases, and minoxidil and dutasteride might also contribute to the edema. This study is the largest case series on this specific side effect, providing valuable information for clinicians performing mesotherapy. Dermatologists should be aware of this potential adverse effect, as it can significantly impact patients.
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