Autologous Adipose-Derived Stem Cell Versus Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: Efficacy, Side Effects, and Safety

January 2018 in “ Journal of clinical & experimental dermatology research ”

Mostafa Kadry, Wael Abou El-Kheir, Medhat Shalaby, Ahmed Rashad El Shahid, Hala G. Metwally

autologous adipose-derived stem cells platelet-rich plasma androgenetic alopecia terminal hair count intermediate hair count hair caliber erythema AT-ASCs PRP AGA

Studysummary This study suggests that AT-ASCs significantly improve terminal and intermediate hair counts and hair caliber in androgenetic alopecia more than PRP, though with more side effects like headache and erythema. Our plain-language summary of this paper — not a Tressless recommendation.

In the 2018 study involving 60 patients with androgenetic alopecia (AGA), the efficacy, side effects, and safety of autologous adipose-derived stem cells (AT-ASCs) and platelet-rich plasma (PRP) were compared. Patients received three treatment sessions at one-month intervals and were followed up after three months. The AT-ASCs group showed a highly significant improvement in terminal hair count, intermediate hair count, and hair caliber (all p<0.001), but experienced more side effects like headache and erythema. The PRP group also had a significant improvement in terminal hair count (p=0.037) with minimal side effects. The study concluded that both treatments are effective and safe for AGA, with AT-ASCs providing more significant improvements but also more side effects.

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