Autologous Adipose-Derived Stem Cell Versus Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: Efficacy, Side Effects, and Safety

January 2018 in “ Journal of clinical & experimental dermatology research ”

Mostafa Kadry, Wael Abou El-Kheir, Medhat Shalaby, Ahmed Rashad El Shahid, Hala G. Metwally

autologous adipose-derived stem cells platelet-rich plasma androgenetic alopecia terminal hair count intermediate hair count hair caliber erythema AT-ASCs PRP AGA

TLDR Both fat-derived stem cells and platelet-rich plasma are effective and safe for hair loss, but stem cells give better results with more side effects.

In the 2018 study involving 60 patients with androgenetic alopecia (AGA), the efficacy, side effects, and safety of autologous adipose-derived stem cells (AT-ASCs) and platelet-rich plasma (PRP) were compared. Patients received three treatment sessions at one-month intervals and were followed up after three months. The AT-ASCs group showed a highly significant improvement in terminal hair count, intermediate hair count, and hair caliber (all p<0.001), but experienced more side effects like headache and erythema. The PRP group also had a significant improvement in terminal hair count (p=0.037) with minimal side effects. The study concluded that both treatments are effective and safe for AGA, with AT-ASCs providing more significant improvements but also more side effects.

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