Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles

September 2021 in “ Colloids and surfaces. B, Biointerfaces ”

Ricardo Ferreira‐Nunes, Marcílio Cunha-Filho, Guilherme M. Gelfuso

spironolactone polymeric nanoparticles poly-ε-caprolactone methacrylic acid/methyl methacrylate copolymer alopecia hair follicles PCL EL100

Studysummary This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.

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