Hair Follicles as a Target Structure for Nanoparticles

    Jürgen Lademann, Fanny Knorr, Heike Richter … Alexa Patzelt
    Studysummary This review examines the potential of nanoparticles for localized drug delivery via hair follicles but reports no new clinical results, with the authors noting a lack of commercial development despite research progress.
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    Research cited in this study 11

    1. Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality? Skin pharmacology and physiology · 2013
    2. Triggering of Drug Release of Particles in Hair Follicles Journal of controlled release · 2012
    3. Study of the Biological Function and Penetration Pathways of the Mouse Epidermal Growth Factor Ethosomal Delivery System Experimental Dermatology · 2011
    4. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    5. Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions European journal of pharmaceutics and biopharmaceutics · 2009
    6. Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    7. The Role of Hair Follicles in the Percutaneous Absorption of Caffeine BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2007
    8. Investigation of Differences in Follicular Penetration of Particle- and Nonparticle-Containing Emulsions by Laser Scanning Microscopy Laser Physics · 2006
    9. Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin Journal of Investigative Dermatology · 2005
    10. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    11. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004