Hair Follicles: Strategic Targets for Promoting Hair Growth

    Nakognon Awa TUO-KOUASSI, Kakwokpo Clémence N’GUESSAN-GNAMAN, Sandrine AKA-ANY-GRAH, Apo Laurette ANIN, Arthur José LIA, Alain N’Guessan, Ismaël DALLY, Marcelle Adjoa Yao, Armand Koffi
    TLDR Targeting hair follicles can effectively promote hair growth and treat hair disorders.
    The hair follicle is a complex micro-organism that serves as a promising pathway for targeted delivery of active substances to treat hair disorders. Its unique structure, including a funnel-shaped architecture and associated glands, enhances skin penetration and supports sustained release of compounds. The follicle's dynamic biological activity, with its cyclic growth pattern, allows for timed and localized drug delivery. Recent advances in delivery technologies, such as nanoparticles and liposomes, have optimized transfollicular targeting, improving therapeutic efficacy while minimizing systemic exposure. This article reviews the follicle's characteristics, its role in transfollicular uptake, and advances in delivery technologies for cosmetic and medical purposes.
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