Novel Strategies for Androgenetic Alopecia Therapy: Integrating Multifunctional Plant Extracts with Nanotechnology for Advanced Cutaneous Drug Delivery

    September 2025 in “ Pharmaceutics
    R. Diao, Meiqi Sun, Ningxin Zhang, Xinqian Liu, Ping Song
    TLDR Combining plant extracts with nanotechnology may improve hair loss treatments.
    This review explores innovative strategies for treating androgenetic alopecia (AGA) by integrating multifunctional plant extracts with nanotechnology to enhance drug delivery. Current treatments like minoxidil and finasteride have limitations, prompting the exploration of plant extracts such as Saw Palmetto, Cacumen Platycladi, and Panax Ginseng, which show promise due to their anti-androgenic, anti-inflammatory, and hair growth-promoting properties. Nanocarriers like nanoemulsions and liposomes can improve the stability and targeted delivery of these extracts, potentially increasing therapeutic efficacy and patient compliance. However, challenges such as formulation stability and regulatory scrutiny remain, and further large-scale, long-term studies are necessary to confirm the efficacy and safety of these novel approaches.
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